Which populations does safety pharmacology seek to predict safety for?

Which populations does safety pharmacology seek to predict safety for?

• A. Plants
• B. Insects
• C. Humans and animals
• D. Microorganisms

Answer: (C)

Safety pharmacology is about predicting a drug’s adverse effects in people by studying potential toxicities in animal models and in vitro systems that reflect human physiology. The goal is to forecast safety for humans, using data from animals as models of how a drug might affect human organ systems. Animals are included because many physiological pathways are similar enough to humans to reveal potential risks before human exposure. Plants, insects, and microorganisms aren’t the populations safety pharmacology aims to predict for in clinical safety assessments, though they may be investigated in other fields.

Safety pharmacology is about predicting a drug’s adverse effects in people by studying potential toxicities in animal models and in vitro systems that reflect human physiology. The goal is to forecast safety for humans, using data from animals as models of how a drug might affect human organ systems. Animals are included because many physiological pathways are similar enough to humans to reveal potential risks before human exposure. Plants, insects, and microorganisms aren’t the populations safety pharmacology aims to predict for in clinical safety assessments, though they may be investigated in other fields.